It is a malignancy that affects the body's immune system, the lymphatic system, one of the cancer types that are most easily treated. A lymphocyte, a kind of white blood cell, experiences a DNA alteration that causes Hodgkin lymphoma. Depending on the specific needs of the patient, chemotherapy or radiation may be used as a form of treatment for Hodgkin lymphoma. Although it is not advised for first-line therapy, transplantation of stem cells is another possibility for treatment.

Hodgkin lymphoma begins when a white blood cell undergoes an aberrant DNA alteration that transforms it into a lymphoma cell, which if left untreated leads to the unchecked proliferation of malignant lymphocytes because of the crowding out of healthy white blood cells by these malignant cells, the immune system is unable to properly fight infection. The lymph nodes, which are found all over our bodies in the lymphatic system are where lymphoma cells typically proliferate and create masses. Additionally, lymphoid tissue in other parts of the body can serve as a home for lymphoma cells. Reed-Sternberg cells are a feature of Hodgkin lymphoma that set it apart from other lymphoma subtypes. Hodgkin cells are a different type of cell linked to the illness. Hodgkin cells are smaller than RS cells but larger than regular lymphocytes. These variations can be seen under a microscope and they can be further recognised by unique pathological tests.

Lymphocytes, a type of white blood cell that fights infection, undergo DNA alterations. When the other cells would normally die, the DNA modifications instruct the cells to reproduce quickly and to stay alive. Hodgkin's lymphoma comes in a variety of forms. The specific aetiology of Hodgkin lymphoma is unknown in the majority of cases, although the following risk factors may enhance a person's chance of getting the disease: Epstein-Barr virus infection in the past: Some cancers including HL, are linked to the mononucleosis-causing Epstein-Barr virus which also causes mononucleosis. Early childhood Epstein-Barr virus infection or "mono" in adolescence both raise the likelihood of developing HL. However, despite the fact that many people have EBV infection, very few go on to develop HL. Adolescents, young adults, and older individuals have the highest rates of HL. Males are slightly more likely to develop HL. The risk of HL may be increased if a parent or sibling has the disease.

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Clinical Pathology & Laboratory Medicine Peer- reviewed which will be dedicated to advancing diagnosis of diseases based on the laboratory analysis of bodily fluids, such as blood, urine, and tissue homogenates or extracts using the tools of biochemistry, microbiology, haematology and molecular pathology.

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Clinical Pathology & Laboratory Medicine