Elephantiasis in a Patient with EMO Syndrome

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Exophthalmos, myxedema and osteoarthropathy (EMO) comprise the triad known as EMO syndrome, which is a rare extrathyroid syndrome seen in patients suffering from hyperthyroidism, occurring in less than 1% of patients suffering from autoimmune thyroid disease. In its classic presentations, manifestations of Graves’ disease (GD) begins with thyroid dysfunction, followed by Graves’ ophthalmopathy (GO) in 30% of patients several months later and subsequent thyroid dermopathy in 1% to 4% of patients several months to years later. НyroLd dermopathy is a rare manifestation of GD. It occurs in less than 5% of all patients with GD. Much less common is the elephantiasic variant as seen in this case, which is a rare and extreme subtype of Graves’ dermopathy. As reported by the classic Mayo Clinic series, it only accounts for 1 of 150 patients with skin involvement. We here describe an unusual case of EMO syndrome associated with severe elephantiasic subtype of pretibial myxedema, which occurs in less than 1% of patients with thyroid dermopathy

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Denise Williams
Editorial Manager     
Journal of Thyroid Disorders & Therapy
E-mail id: thyroid@emedscience.org